[Inositol Efficacy] Essential for women of childbearing age, 3 benefits of Inositol

[Inositol Efficacy] Essential for women of childbearing age, 3 benefits of Inositol

Dec 11, 2024Ehotyshamull Joy
Pharmacist who reads papers
Why is inositol important for women of childbearing age?
1. Improves insulin resistance
2. Decreased ovulation induction period
3. Induction of regular menstruation
Hello. I'm a pharmacist Jinny.
 
Polycystic ovary syndrome is a health concern for many women of childbearing age. Polycystic ovary syndrome is an endocrine disorder that is common in women of childbearing age, and refers to ovulation abnormalities, clinical hyperactivity of male hormones, or polycystic ovaries observed on ultrasound. Patients with polycystic ovary syndrome may develop infertility due to abnormal menstrual and ovulation disorders, as well as insulin resistance and hirsutism.
 
Recently, it has been known that inositol intake can help with the symptoms of polycystic ovary syndrome, and more and more people are looking for inositol. Inositol is a substance that constitutes phospholipids in cell membranes in our body and is involved in signaling and insulin metabolism.
 
Therefore, today we will take a closer look at exactly what benefits inositol has through a paper.
1. Improves insulin resistance
Insulin resistance is a condition in which insulin's ability to lower blood sugar decreases, making it impossible for cells to effectively burn glucose. When insulin resistance increases, glucose production is not controlled in the liver, and glucose utilization in the muscles or storage as fat is poor, so blood sugar remains high. Because high insulin resistance is also a major symptom of polycystic ovary syndrome, women with polycystic ovary syndrome are known to have a higher risk of developing type 2 diabetes than women without polycystic ovary syndrome.
In this regard, a paper was published in 2017 in Gynecological Endocrinology that studied the effects of ingestion of inositol on insulin resistance [1].
"At 21 days after 12 weeks of myo inositol (MYO) administration, serum progesterone (female sex hormone) levels increased significantly, and fasting insulin, fasting glucose, and homeostatic models of insulin resistance (HOMA-IR) decreased."
2. Decreased ovulation induction period
 

When women are preparing to conceive, they often check their ovulation cycle. This is because ovulation is the time when the egg is released out of the ovary and is an important stage for pregnancy. So, if ovulation doesn't happen normally, it can also cause infertility.

 

In this regard, a study was published in 2017 with the results of a study showing that inositol intake significantly shortened the period of ovulation induction [2].

"Myo administration increases clinical pregnancy rates and decreases total r-FSH (follicle-stimulating hormone) dose and duration of ovulation induction."
3. Induction of regular menstruation

If you are a healthy woman of childbearing age, you will have your period every 26-32 days. On the other hand, amenorrhea, a typical symptom of polycystic ovary syndrome, is when a woman who had menstruation has not had a menstrual period for more than three times the previous menstrual cycle, or has not had a menstrual period for more than six months.

 

In this regard, a paper published in Gynecological Endocrinology in 2007 revealed the results of a study showing that women with polycystic ovary syndrome restored their menstrual cycles when they took inositol [3].

"Of the 25 patients (88%), they regained at least one spontaneous menstrual cycle during treatment, and 18 of them (72%) maintained normal ovulation activity during the follow-up period."

 

Today, we looked at the benefits of taking inositol in a paper. Lastly, if you are overweight or obese and have polycystic ovary syndrome, it is recommended that you combine diet and exercise as losing weight will help improve your symptoms.

 

I hope you have a healthy day in body and mind. It was Jinny.

 

[1,2] Özlen Emekçi Özay, Ali Cenk Özay, Erkan Çağlıyan, Recep Emre Okyay & Bülent Gülekli (2017) Myo-inositol administration positively effects ovulation induction and intrauterine insemination in patients with polycystic ovary syndrome: a prospective, controlled, randomized trial. Gynecol Endocrinol. 33(7):524-528.
[3] Papaleo, E., Unfer, V., Baillargeon, J. P., De Santis, L., Fusi, F., Brigante, C., Marelli, G., Cino, I., Redaelli, A., & Ferrari, A. (2007). Myo-inositol in patients with polycystic ovary syndrome: a novel method for ovulation induction. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 23(12), 700–703.

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