[Effects of Coenzyme Q10] 3 Benefit of CoQ10,  That Blocks Free Radicals, the Main Cause of Aging

[Effects of Coenzyme Q10] 3 Benefit of CoQ10, That Blocks Free Radicals, the Main Cause of Aging

Dec 03, 2023KimSunhyo

[Effects of Coenzyme Q10] 3 Benefit of CoQ10,

Blocks Free Radicals, the Main Cause of Aging

Coenzyme Q10 (CoQ10)
If Aging is Progressing, You Should Pay Attention to Coenzyme Q10
This content is health information about ingredients and not directly related to a specific product.
Effects of Coenzyme Q10
1. Improves high blood pressure
2. Improves blood sugar control
3. Improves exercise performance

Hello, I am Jinny, a pharmacist.

Physical aging is a human fate that neither I, the person writing this article, nor you, the readers, can avoid. In general, our body's functions begin to decline at the age of 30, and by the mid-40s, we begin to feel signs of aging centered on our joints, muscles, and eyes. As the overall function of our body's organs deteriorates, we are less able to respond to external stress and become increasingly vulnerable to diseases.

The level of functional decline of body organs due to aging varies depending on how well the cells within them function. When cell function is active, the level of functional decline is lower. In other words, there are no particular signs of aging. This is why Coenzyme Q10, the ingredient we will introduce today, is called a representative anti-aging nutrient.

Coenzyme Q10 is a nutrient that plays an essential role in the proper functioning of mitochondria, the energy factories within cells, while protecting cells through its antioxidant properties. The benefits of ingestion have also been studied from various angles, and the Ministry of Food and Drug Safety has recognized Coenzyme Q10 as a functional ingredient for blood pressure and antioxidant functions, and academic circles have also consistently reported its benefits against aging, adult diseases, and cardiovascular diseases.

Today, through academic research on Coenzyme Q10, a representative anti-aging nutrient, we will look at how Coenzyme Q10 can contribute to preventing aging in our body.

1. Improves High Blood Pressure

According to the National Health Insurance Corporation, the number of patients with high blood pressure in Korea last year was 13.74 million. This means that one in four adults over the age of 20 has high blood pressure. High blood pressure, which refers to a condition in which the pressure of arterial blood flow is abnormally high, is the main cause of aging of blood vessels and is also a phenomenon that occurs due to aging of blood vessels. It can also easily spread to complications such as angina, myocardial infarction, and cerebrovascular disease.

The antihypertensive benefits of Coenzyme Q10, a representative anti-aging nutrient, have been reported in academic circles since 1994. P Langsjoen and researchers (1994) evaluated the effect of coenzyme Q10 intake on blood pressure in 109 patients with essential hypertension and reported that improvements in systolic and diastolic blood pressure were confirmed.

“Overall NYHA (New York Heart Association) functional class improved from a mean of 2.40 to 1.36 (P<0.001), and 51% of patients completely discontinued one to three antihypertensive medications at a mean of 4.4 months after starting CoQ10.”

Reference :   P Langsjoen, P Langsjoen, R Willis, K Folkers. (1994) Treatment of essential hypertension with Coenzyme Q10. Mol Aspects Med. 15:S265-72.
2. Improves Blood Sugar Control

Among the functions that decline with aging is the ability to regulate blood glucose levels. Especially, it is known that the ability to control postprandial blood sugar levels steadily declines every 10 years after the age of 50. This phenomenon is interpreted as the result of a comprehensive reflection of various factors such as increased visceral fat, decreased muscle mass, and decreased insulin sensitivity that accompany biological aging.

DeFronzo, R. A. (2004). Pathogenesis of type 2 diabetes mellitus. Medical clinics, 88(4), 787-835.

However, recently, a hypothesis has been raised that dysfunction of intracellular mitochondria due to aging is the fundamental cause of the decline in blood sugar control ability. Accordingly, the blood sugar control benefits of Coenzyme Q10, an important nutrient for mitochondrial function, were evaluated. \ A human application test targeting 50 diabetic patients reported the benefits of Coenzyme Q10 in improving blood sugar control.

“The results of this study show that supplementation with coenzyme Q10 for 12 weeks can improve glycemic control regardless of lipid profile in patients with diabetes.”

Reference :  Zahedi, H., Eghtesadi, S., Seifirad, S., Rezaee, N., Shidfar, F., Heydari, I., ... & Jazayeri, S. (2014). Effects of CoQ10 supplementation on lipid profiles and glycemic control in patients with type 2 diabetes: a randomized, double blind, placebo-controlled trial. Journal of Diabetes & Metabolic Disorders, 13(1), 1-8.
3. Improves Exercise Performance

Loss of muscle mass, which was previously pointed out as one of the causes of the decline in blood sugar control ability, is also a natural phenomenon due to aging. Since muscle mass continues to decrease starting at age 30, experts always suggest exercise as the basis for maintaining health. However, the decline in cardiorespiratory function, muscle, and skeletal function due to aging is also a factor that makes exercise difficult.

As a representative anti-aging nutrient, Coenzyme Q10 is known to affect exercise performance. Cooke, M, and researchers who evaluated the effect of single or continuous intake of Coenzyme Q10 on exercise performance reported that intake of Coenzyme Q10 improved exercise performance in both aerobic and anaerobic exercise.

“Continuous supplementation of coenzyme Q10 increased plasma coenzyme Q10 concentration and increased exercise time when fatigue was felt. These results indicate that coenzyme Q10 supplementation affects exercise performance in various types of exercise.”

Reference :  Cooke, M., Iosia, M., Buford, T., Shelmadine, B., Hudson, G., Kerksick, C., ... & Kreider, R. (2008). Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. Journal of the International Society of Sports Nutrition, 5(1), 8.

Today we learned about Coenzyme Q10, a representative anti-aging nutrient. It is an ingredient that has many benefits, not only for blood pressure and blood sugar, but also for exercise performance. If you have ever had a moment when you feel your age, it would be a good idea to pay attention.

Additionally, if you are taking Coenzyme Q10, we recommend taking it after a meal rather than on an empty stomach, and in the morning or during the day rather than in the evening. Additionally, most human trials evaluate intake over a period of 6 months, so it is important to continue consuming it.

I hope you have a healthy day both physically and mentally. This was Jinny.

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