[Glutathione Synergy Ingredients] 3 Ingredients That Help a Powerful Antioxidant, Glutathione

Dec 03, 2023KimSunhyo

[Glutathione Synergy Ingredients] 3 Ingredients That Help a Powerful Antioxidant, Glutathione

Glutathione

3 Ingredients That Help a Powerful Antioxidant, Glutathione

This content is health information about ingredients and not directly related to a specific product.

Glutathione Synergy Ingredients

1. Cysteine, which makes up glutathione
2. Vitamin E, which protects glutathione
3. Silymarin, which boosts glutathione

Hello, I am Jinny, a pharmacist.

I think the ingredient that has been receiving the most attention recently is glutathione, well-known as whitening injection. I have also introduced this to you once. Glutathione, a very powerful antioxidant, is widely used in whitening-related dermatological procedures in the form of intravenous injection.

Due to its mechanism of action, intravenous glutathione injection rapidly increases the concentration of a specific substance in the body and achieves the desired effect in a short period of time, but it cannot maintain the high concentration for a long time. Eventually, glutathione levels will drop again after some time.

Therefore, it is a good idea to supplement glutathione with ingredients that can help maintain glutathione concentration. We are going to take a look at three of these ingredients today.

1. Cysteine, Which Makes Up Glutathione

This may be a relatively unfamiliar ingredient. Cysteine is an amino acid containing sulfur (S) and is one of the components of glutathione along with glutamic acid and glycine.

Accordingly, in 2011, a paper was published in Diabetes Care studying the effects of taking cysteine supplements on glutathione synthesis.

“Dietary supplementation of these amino acid precursors (cysteine, glycine) restores partial synthesis of GSH (glutathione) and significantly reduces markers of oxidative stress and oxidative damage.”

Reference : Rajagopal V. Sekhar, Siripoom V. McKay, Sanjeet G. Patel, Anuradha P. Guthikonda, Vasumathi T. Reddy, Ashok Balasubramanyam, Farook Jahoor (2011). Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine. Diabetes Care, 34(1), 162-167.

2. Vitamin E, Which Protects Glutathione

In the body, vitamin E plays a role in protecting cells by preventing the oxidation of other substances by oxidizing itself through oxidation-reduction reactions. Therefore, it is a representative antioxidant substance in the body and is known to form a non-enzymatic antioxidant system together with glutathione.

As research on this antioxidant system accumulates, a study on the correlation between vitamin E and glutathione was reported in Drug Metabolism Reviews in 2003.

“Antioxidants such as vitamin E have a protective effect on glutathione enzymes.”

Reference : Rachel I. M. van Haaften, Guido R. M. M. Haenen, Chris T. A. Evelo, Aalt Bast (2003). Effect of Vitamin E on Glutathione-Dependent Enzymes. Drug Metabolism Reviews, 35, 215-253.

3. Silymarin, Which Boosts Glutathione

When we talk about silymarin, it's commonly associated with milk thistle, a key player in liver health. Silymarin is a mixture of flavonoids found in plants like milk thistle, and it plays a role in protecting and regenerating liver cells and detoxification.

As silymarin's liver-protective effects gained wide recognition, a study in 2014 published in the World Journal of Hepatology focused on silymarin's potential in enhancing glutathione function.

“Silymarin enhances hepatic glutathione production by increasing the availability of cysteine and inducing the synthesis of cysteine while inhibiting the catabolism of cysteine to taurine.”

Reference : Vargas-Mendoza, N., Madrigal-Santillán, E., Morales-González, A., Esquivel-Soto, J., Esquivel-Chirino, C., García-Luna Y González-Rubio, M., Gayosso-de-Lucio, J. A., & Morales-González, J. A. (2014). Hepatoprotective effect of silymarin. World journal of hepatology, 6(3), 144–149.

Today we learned about three ingredients that help glutathione. We plan to introduce ingredients that create more synergy when taken together based on the research paper, so please give us a lot of interest.

I hope you have a healthy day both physically and mentally. This was Jinny.

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