[Effects of Omega-3] If You’re Worried About an Excessive Immune Response, Check Out Omega-3
Nov 13, 2023KimSunhyo
[Effects of Omega-3] If You’re Worried About
an Excessive Immune Response,
Check Out Omega-3
Healthy Immunity Without Excess or Deficiency,
Take Care with ‘This’
This content is health information about ingredients and not directly related to a specific product.
Effects of Omega-3
1. Maintain immune system health 2. Alleviates inflammatory diseases and autoimmune diseases 3. Prevents inflammatory diseases
Hello, I am Jinny, a pharmacist.
As the daily temperature range widens to around 10 degrees, the season change season has begun, where immunity is prone to decline. Not only because it is spring season, but I think many people are paying attention to their immunity these days.
A healthy immune system means there is no deficiency or excess of the immune response. The immune system is a complex mechanism that regulates the body's response to external threats and internal disorders. If the immune response is lacking, resistance to external antigens is lost, and if it is excessive, a chronic inflammatory response occurs, leading to tissue damage and loss of body function.
Today, I would like to introduce you to an ingredient that performs anti-inflammatory functions in the body, normalizes immune system function, and alleviates chronic inflammatory reactions caused by immune system hypersensitivity. This ingredient is the omega-3 which you may be familiar with.
1. Maintain Immune System Health
Since a study was published showing that Natives in Greenland who consume enough omega-3 have lower cholesterol levels and a lower risk of developing heart disease despite not eating a lot of vegetables, academics have concluded that omega-3 supplementation can benefit the human body. Research into its benefits continues. Among them, the effect of omega-3 in preventing autoimmune diseases has been consistently reported.
In January 2002, the results of a meta-study that comprehensively reviewed existing papers on omega-3 was published in Isr Med Assoc J. This study evaluated the function of omega-3 in preventing autoimmune diseases caused by excessive immune response.
“Continuous consumption of omega-3 fatty acids can be seen to have contributed to reducing the incidence of inflammation and autoimmune diseases by suppressing any autoreactive (or hyperreactive) T cells. (omitted) Preventing the risk of autoimmune diseases “The use of omega-3 fatty acids may be recommended.”
Reference : Ergas D, Eilat E, Mendlovic S, Sthoeger ZM (2002) "n-3 fatty acids and the immune system in autoimmunity" Isr Med Assoc J., 4(1), 34-38.
2. Alleviates Inflammatory Diseases and Autoimmune Diseases
The supplementation of omega-3 fatty acids has been reported to contribute to the prevention of autoimmune diseases. Research has been ongoing to assess whether the anti-inflammatory effects of omega-3 are effective in both autoimmune diseases and the severity of inflammatory conditions caused by them.
In December 2002, a meta-analysis that reviewed animal experiments and clinical intervention studies on omega-3 was published in the Journal of the American College of Nutrition. This paper evaluates the functionality of omega-3 in alleviating symptoms of various inflammatory and autoimmune diseases, including their severity
In multiple clinical trials, benefits of omega-3 dietary supplementation have been observed in various human inflammatory and autoimmune diseases, including rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, systemic lupus erythematosus, multiple sclerosis, and migraines. Several placebo-controlled experiments in chronic inflammatory conditions have reported significant advantages, including reduced disease symptoms and decreased use of anti-inflammatory agents for omega-3 supplementation.
Reference : Simopoulos AP (2002) "Omega-3 fatty acids in inflammation and autoimmune diseases." J Am Coll Nutr. 21(6), 495-505
3. Prevents Inflammatory Diseases
As revealed in the study introduced earlier, the anti-inflammatory mechanism of omega-3 is caused by a mechanism that suppresses excessive immune responses. Accordingly, research was conducted to determine whether the anti-inflammatory effect of omega-3 can be maintained even in inflammation that is not caused by an excessive immune response.
In 2014, a study that conducted a large-scale comprehensive analysis of clinical research on omega-3 conducted from 1950 to 2013 was published in PLOS ONE. This study uncovered the anti-inflammatory mechanism of omega-3 in more detail and evaluating its function.
“Our study shows that supplementation with marine-derived n-3 polyunsaturated fatty acids (PUFAs) improves C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor α (TNF-α) in healthy subjects. The significant lowering effect suggests that inflammation-related chronic diseases can be effectively prevented. The anti-inflammatory effect is most effective in non-obese patients. In conclusion, marine-derived n-3 polyunsaturated fatty acid supplementation reduces fasting blood TNF-α. , has a significant lowering effect on IL-6 and CRP.”
Reference : Li K, Huang T, Zheng J, Wu K, Li D (2014), Effect of marine-derived n-3 polyunsaturated fatty acids on C-reactive protein, interleukin 6 and tumor necrosis factor α: a meta-analysis., PLOS ONE, 9(2), e88103.
Today, we briefly looked at the functions of Omega-3 that have been verified by academia.
I hope you have a healthy day both physically and mentally. This was Jinny.