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Isoflavones, why they are recommended for menopausal women
bone resorption
Hello. I'm a pharmacist Jinny.
When it comes to beans, they are widely known as "beef from the field" and are rich in vegetable protein. But there's another treasure hidden in the beans. They are 'isoflavones' called phytoestrogens.
Isoflavones are phytochemicals contained in soybeans and have a molecular structure and efficacy similar to the female hormone estrogen. Therefore, it is highly sought after by women who need to manage menopausal symptoms due to the decrease in estrogen.
Today, we're going to take a look at exactly how isoflavones can help with menopausal symptoms, along with a paper.
After menopause, estrogen decreases, and the central body that regulates body temperature becomes dysfunctional. Typical symptoms of this include a sudden feeling of warming and sweating, as well as hot flashes caused by dilation of blood vessels in the skin. Although it is not life-threatening, it causes great discomfort in the daily life of menopausal women.
In this regard, a report was published in Maturitas in 2011 that studied how isoflavone intake affects the frequency and duration of hot flashes [1].
"The current study provides the first evidence that a single daily dose of 30 mg of synthetic genistein (a type of isoflavone compound) reduces the frequency and duration of hot flashes."
These are not the only symptoms of a decrease in estrogen. Throughout life, the bones in our body repeat the process of absorption and production. At this time, estrogen inhibits the function of thyroid hormones and helps the absorption of calcium along with vitamin D, prevents bone breakdown (bone resorption), and promotes reproduction. Therefore, a decrease in the concentration of estrogen increases the loss of bone mass and therefore increases the risk of developing osteoporosis.
A 2004 study published in the Journal of Women's Health reported on the relationship between isoflavone intake and bone resorption [2]:
"In this study, isolated forms of soy isoflavones were effective in significantly reducing bone resorption in postmenopausal women."
When menopause occurs, not only physical changes appear, but also psychological ones. As the autonomic nervous system is out of balance, you may feel extreme mood swings, and you may become nervous because your anxious and depressed feelings do not go away.
In this regard, a 2016 Archives of Gynecology and Obstetrics reported a paper that studied the effects of isoflavone intake on depressive symptoms in women experiencing menopausal symptoms.
"Low-dose (25 mg/day) isoflavone aglycone significantly reduced symptoms of depression and insomnia in middle-aged Japanese women."
Today, we looked at the benefits of isoflavones in menopausal women's health in a paper. Isoflavones have several benefits, but some people should be cautious about their intake. Since it is mainly derived from soybeans, people who are allergic to soy should be careful about consuming it, and as mentioned earlier, people who are sensitive to estrogen should also be careful because it acts similarly to estrogen.
I hope you have a healthy day in body and mind. It was Jinny.
[1] ] Evans, M., Elliott, J. G., Sharma, P., Berman, R., & Guthrie, N. (2011). The effect of synthetic genistein on menopause symptom management in healthy postmenopausal women: A multi-center, randomized, placebo-controlled study. Maturitas, 68(2), 189–196.
[2] Harkness, L. S., Fiedler, K., Sehgal, A. R., Oravec, D., & Lerner, E. (2004). Decreased Bone Resorption with Soy Isoflavone Supplementation in Postmenopausal Women. Journal of Women’s Health, 13(9), 1000–1007.
[3] Hirose, A., Terauchi, M., Akiyoshi, M., Owa, Y., Kato, K., & Kubota, T. (2016). Low-dose isoflavone aglycone alleviates psychological symptoms of menopause in Japanese women: a randomized, double-blind, placebo-controlled study. Archives of gynecology and obstetrics, 293(3), 609–615.
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