Vitamin C can be both natural and synthetic. Each has a different position of support. The group that emphasizes synthetic vitamin C emphasizes research showing that vitamin C does not differ in its benefits, such as bioavailability, whether synthetic or natural. It is clearly different from vitamins A and E, which emphasize naturalness. It is wrong to say that vitamin C is synthesized from coal tar, which is a by-product of making petroleum. This is related to the process of making some vitamin supplements, such as B vitamins, and has nothing to do with vitamin C. Today, vitamin C is usually synthesized by fermenting glucose from corn or potatoes. That's why those who emphasize synthesis emphasize that even synthetic vitamin C is made from plant-based sources.
However, those who emphasize natural criticize the claim that vitamin C = ascorbic acid. In addition to ascorbic acid, vitamin C must be combined with various forms of plant components such as flavonoids and coenzymes to be effective. Vitamin C is also a natural vitamin supplement that is as close to the form of food as possible. Natural vitamin C formulations are made from real fruits, such as acerola and lemons, and are packaged in pills. Naturally, the cost is high, and the size of the pills is large, making it difficult to swallow. Best of all, natural vitamin C has too little of the actual vitamin C in a single pill. Low purity is one of the disadvantages of natural vitamin preparations.
I don't think vitamin C needs to be as sensitive as vitamin A and E to whether it's synthetic or natural. However, when large amounts of high-purity vitamin C are injected into the vein at once, synthesis is advantageous in all aspects, such as cost and administration process. However, if you are going to eat a small amount every day, I would recommend natural vitamin C on the assumption that you can afford it.
It's also good to know about the neutral vitamin C that is currently available on the market when it comes to vitamin C preparations. As you know, vitamin C has a low acidity, which gives it a sour taste and can cause stomach upset in people who have an upset stomach or are sensitive. In this case, the so-called neutral vitamin C, which combines with calcium minerals to reduce acidity, helps. It does not irritate the stomach, so it can be taken before meals or on an empty stomach. The disadvantage is that they are more expensive than regular vitamin C preparations. There is no difference between neutral vitamin C preparations and regular vitamin C preparations in terms of their concentration in the blood or excretion in the urine. However, studies have shown that neutral vitamin C preparations are beneficial in terms of increasing the concentration of vitamin C in white blood cells. If you have a sensitive stomach, you may want to opt for a neutral vitamin C preparation.
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