What are the three ingredients that help powerful antioxidants, glutathione?
💊 Pharmacist Rani 💊
A former pharmacist with a constitution researching formulation rather than a
'Strict Manager' style of all health information
Ingredients that help maintain glutathione levels
01. Cysteine constituting glutathione
02. Vitamin E to protect glutathione
03. Silymarin to enhance glutathione
Hello. I am a pharmacist who reads a dissertation.
Glutathione, which is well-known for white jade injection, is the ingredient that has received the most
attention recently. Glutathione, a very powerful antioxidant, is widely used in
dermatological procedures related to whitening in the form of an intravenous
Glutathione intravenous injection achieves the desired action in a
short period of time by rapidly increasing the concentration of a specific
substance in the body through its mechanism of action, but does not maintain
the high concentration for a long time. Eventually, your glutathione levels will
drop again after a while.
Therefore, it is good to supplement with glutathione ingredients that can help
maintain glutathione concentration. Let's take a look at three of these
01. Cysteine constituting glutathione
It must be a relatively unfamiliar ingredient. Cysteine is an amino acid containing sulfur (S) and is one of the constituents of glutathione along with glutamic acid and glycine.
Therefore, in 2011 Diabetes Care published a paper that studied the effects of
cysteine supplementation on glutathione synthesis.
“Dietary supplementation of these amino acid precursors (cysteine, glycine)
restores partial synthesis of GSH (glutathione) and significantly reduces
oxidative stress and markers of oxidative damage.”
References: Rajagopal V. Sekhar, Siripoom V. McKay, Sanjeet G. Patel, Anuradha P. Guthikonda, Vasumathi T. Reddy, Ashok Balasubramanyam, Farook Jahoor (2011). Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine. Diabetes Care, 34(1), 162-167.
02. Vitamin E that protects glutathione
In the body, vitamin E plays a role in protecting cells by preventing oxidation of
other substances by being oxidized through oxidation-reduction reactions. Therefore, as a representative antioxidant in the body, it is
known to constitute a non- enzymatic antioxidant system together with glutathione.
As research on this antioxidant system has accumulated, a study on the
relationship between vitamin E and glutathione was reported in Drug
Metabolism Reviews in 2003.
“Antioxidants like vitamin E have a protective effect on glutathione enzymes.”
References: Rachel I. M. van Haaften, Guido R. M. M. Haenen, Chris T. A. Evelo, Aalt Bast (2003). Effect of Vitamin E on Glutathione-Dependent Enzymes. Drug Metabolism Reviews, 35, 215-253.
03. Silymarin to strengthen glutathione
When it comes to silymarin, it is known as an ingredient in milk thistle, which is a
representative of liver health. Silymarin is a mixture of flavonoids found in milk
thistle, such as milk thistle, that protects and regenerates the liver and acts as
As silymarin's hepatoprotective action has been widely studied, a study
published in the World journal of hepatology in 2014 focused on silymarin's
"Silymarin enhances hepatic glutathione production by inducing cysteine
synthesis while increasing cysteine solubility and inhibiting cysteine taurine
References: Vargas-Mendoza, N., Madrigal-Santillán, E., Morales-González, A., Esquivel-Soto, J., Esquivel-Chirino, C., García-Luna Y González-Rubio, M., Gayosso -de-Lucio, JA, & Morales-González, JA (2014). Hepatoprotective effect of silymarin. World journal of hepatology, 6(3), 144–149.
Today, we learned about three ingredients that help glutathione. In the future,
we will introduce more synergistic ingredients based on the thesis, so please
We will always come back with useful content.
always be healthy 😀
Don't forget to check out the product that contains this useful ingredient!