[Efficacy of aloe gel] From preventing colon cancer to skin elasticity? 3 Benefits of Aloe Gel

Aloe gel, which is a multi-talented beauty, is good to apply, but even better to eat

Aloe Gel  Benefits
1. Improvement of peptic ulcer
disease 2. Improvement of inflammatory bowel disease
3. Improvement of facial wrinkles and elasticity

This is Jinny, the pharmacist.

A skincare ingredient that is often sought after in the summer is, of course, aloe. Haven't you all experienced applying a thick layer of aloe soothing gel stored in the refrigerator to soothe reddened skin from the summer heat and UV rays? As such, the familiar skincare ingredient aloe is actually an ingredient with more benefits when ingested.

In particular , research results have accumulated that the polysaccharides abundantly contained in 'aloe gel', which refers to the gel part from which the peel of the Aloe vera leaf is removed , have the effect of improving immunity, intestinal health, and skin health when taken orally . In addition, recently, research results have been reported in the academic world that the intake of aloe gel can improve the intestinal mucosa and regulate the intestinal immune system to suppress the occurrence of colon tumors and contribute to the prevention of colon cancer.

[Source] Im, SA, Kim, JW, Kim, HS, Park, CS, Shin, E., Do, SG, ... & Lee, CK (2016). Prevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by processed Aloe vera gel. International immunopharmacology, 40, 428-435.


According to the accumulated research results of the academic world, Korea's Ministry of Food and Drug Safety also recognizes the triple functionality of immunity enhancement, skin health, and intestinal health for aloe gel containing more than 3% of the core ingredient 'polysaccharide'. . As the benefits of ingestion are complex ingredients, today we will look at what kind of people should pay attention to aloe gel through a human application test.

 

1. Improvement of peptic ulcer

When the three functions of aloe gel – immunity, skin health, and intestinal health improvement – ​​work in combination, the body organ that can expect the greatest benefit is the digestive system. The digestive system is made up of mucosal tissue and is easily invaded by bacteria as an organ that accepts food from the outside, so proper immunity and the health of the mucous membrane (skin) are important to maintain health.


Academics have also focused on this aspect and evaluated the effects of aloe vera gel intake on actual peptic ulcer patients In this study, which confirmed improvement in severe peptic ulcer disease following 45 days of aloe vera gel consumption, the authors present the study's conclusions as follows:

" Many patients have fully recovered from acute peptic ulcer disease, which is attributed to aloe gel's inhibition of hydrochloric acid secretion, pepsin anabolism, and general detoxification ... Aloe vera gel protects the stomach wall from acid when it is irritated or damaged. Aloe vera gel is not only easily absorbed from the stomach, but also neutralizes excess stomach acid and promotes a healing environment for ulcers. ”
Reference paper: Rajendran, A., Sobiya, G., & Gnanavel, I. (2008). Study on the effective supplementation of Aloe vera gel antacid to peptic ulcer patients. Res J Medicine & Med Sci, 3(2), 132-134.

 

2. Improves Inflammatory Bowel Disease

Even before the functionality of aloe gel was scientifically identified, aloe gel was a food ingredient that was routinely consumed for skin health and intestinal health. In particular, in the Western world, it seems that folk remedies of consuming aloe have become popular not only for the improvement of constipation, but also for the improvement of inflammatory bowel disease accompanied by abdominal pain, diarrhea, and fever.


The popularity of these folk remedies has prompted the academic community to examine the benefits and safety of aloe gel intake for patients with inflammatory bowel disease. Accordingly A human application test study was conducted to evaluate the effects of aloe vera gel intake on 44 patients with inflammatory bowel disease. are doing

" Frequent clinical improvements were observed in the 4-week aloe vera group compared to the placebo group. In addition, the aloe vera gel reduced histological disease activity and was found to be safe. "
Reference paper Langmead, L., Feakins, RM, Goldthorpe, S., Holt, H., Tsironi, E., De Silva, A., ... & Rampton, DS (2004). Randomized, double blind, placebo controlled trial of oral aloe vera gel for active ulcerative colitis. Alimentary pharmacology & therapeutics, 19(7), 739-747.

 

3. Improvement of facial wrinkles and elasticity

Through the studies introduced earlier, I think you should have fully understood the contribution of the complex functionality of aloe gel to improving inflammation in the digestive system and maintaining mucosal health. However, as it is a widely used ingredient in skin care, it would be disappointing if we did not check whether it can help the health of 'facial skin' even when ingested.


In 2009, the results of a human application test that evaluated the effects of aloe vera gel intake for 90 days on 30 healthy female subjects over the age of 45 were already reported in the academic world. In this study, the improvement of facial wrinkles and skin elasticity according to the intake of aloe gel was confirmed , and the authors reveal the results of the study as follows.

" Aloe gel significantly improves wrinkles and elasticity in photoaged human skin by increasing collagen production in photoaged skin and reducing the expression of the MMP-1 gene that decomposes collagen."
Reference Paper Cho, S., Lee, S., Lee, MJ, Lee, DH, Won, CH, Kim, SM, & Chung, JH (2009). Dietary Aloe vera supplementation improves facial wrinkles and elasticity and it increases the type I procollagen gene expression in human skin in vivo. Annals of dermatology, 21(1), 6-11.

 

Today, we learned about aloe gel that can be applied or eaten. While preparing to introduce aloe gel this time, I searched and found that there were people who were already aware of these benefits and were taking aloe juice or aloe leaves. As such, it would be more advantageous to choose 'Aloe Gel', a health functional food whose total polysaccharide content has been confirmed by the Ministry of Food and Drug Safety. 

I hope you have a healthy day in body and mind. It was Jinny.