There are two forms of coenzyme Q10: ubiquinone and ubiquinol. First, ubiquinone is a form of coenzyme Q10 that is synthesized by the body, and common coenzyme Q10 preparations belong to this form. The form in which ubiquinone is altered to be used in the body is ubiquinol.
1. So, is it better to take CoQ10 in its ubiquinol form?
When ingested, ubiquinol passes through the stomach and small intestine, and most of it is converted back into ubiquinone. In addition, there is no need to stick to ubiquinol because ubiquinone is easily converted into ubiquinol in the body.
Here's how to increase the absorption rate of CoQ10. Since coenzyme Q10 is fat-soluble, it is best to take it after a meal rather than on an empty stomach. It's also a good idea to take it with omega-3s.
2. Is coenzyme Q10 good for skin health?
Free radicals are also the cause of skin aging. Free radicals are known to cause damage to skin cells and tissues. This accelerates skin aging, such as loss of elasticity, wrinkles and blemishes, and freckles. Antioxidants protect skin cells by removing these free radicals.
Coenzyme Q10 is one of the most powerful antioxidants and has been shown to have a positive effect on skin health. In fact, when coenzyme Q10 was taken at a dosage of 50mg or 150mg for 12 weeks, it was effective in improving wrinkles and smoothing skin texture.[source]
Therefore, taking CoQ10 may also benefit skin health.
Among hyperlipidemia treatments, statin drugs have been shown to reduce coQ10 levels in the body through several studies. Statins prevent cholesterol from being synthesized in the liver because coenzyme Q10 is synthesized in the same pathway as cholesterol. [source]
Because of this, the antioxidant activity of the lipid membrane is interfered with, which can lead to muscle-related side effects. [source] Therefore, supplementation with CoQ10 may help with these side effects. In fact, patients who were taking statin drugs who had muscle pain side effects were supplemented with 100 mg of coenzyme Q10 per day and their pain was reduced. [source]
In addition, coenzyme Q10 is known to be effective in reducing cholesterol levels when consumed. A study in patients with coronary artery disease* showed that coenzyme Q10 significantly reduced total cholesterol and increased HDL cholesterol levels. [source]
4. Is Coenzyme Q10 good for infertile couples?
Infertility is a condition in which a woman has not been able to conceive despite living a normal married life. Any abnormality in any of the processes from the development of germ cells to the fertilization of sperm and eggs, the development of the fertilized embryo, and the implantation of the embryo in the uterus can lead to infertility. Of these, coenzyme Q10 is associated with the development of embryos.
Coenzyme Q10 acts as an antioxidant, as mentioned above, and also plays an important role in the conversion of carbohydrates and fats into energy inside the mitochondria. Therefore, if coenzyme Q10 is deficient, energy cannot be produced well and free radicals cannot be removed, resulting in damage to mitochondrial DNA.
These mitochondria are the organs that supply the energy needed for the fertilized embryo to divide and develop. Therefore, if there is an abnormality in the mitochondria, the development rate of the embryo may slow down or the embryo's cell division may be stopped. For this reason, for women struggling with infertility, taking CoQ10 may be beneficial.
I would like to introduce the results of the human body application test in this regard. Participants who took 200 mg of coenzyme Q10 for 60 days had a higher pregnancy rate and a lower miscarriage rate than the placebo group. In addition, studies have shown that the risk of developing preeclampsia, which is also the cause of fetal growth failure and fetal death, has decreased. [source]
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