[Probiotics Episode 3] Leaky Gut Syndrome causes various allergies and autoimmune diseases | Dr. Esther Lyuh

leaky gut, leaky gut syndrome

Why are our intestines leaking...

Do you know that your intestines are leaking? Originally, the intestinal mucosal cells are densely and firmly attached to each other, preventing feces from entering the body directly. However, for various reasons, when the gaps between these intestinal mucosal cells become loose and gaps form, bacteria, and toxins in the feces enter the blood through these gaps and affect various parts of the body.  This is the leaky gut syndrome that has recently emerged.

It's not just leaky gut

The leaky gut syndrome is known to be involved in a variety of things, from allergic diseases such as atopy to life-threatening sepsis.  For example, many people die of sepsis after surgery or in an intensive care unit. Sepsis is when germs enter the bloodstream or cause severe inflammatory reactions in organs throughout the body. So, to prevent sepsis, if the elderly undergo open surgery, I recommend taking lactic acid bacteria before surgery to reduce harmful bacteria before undergoing surgery.

Common symptoms of a leaky gut
One of the common symptoms of the leaky gut syndrome is various allergic reactions What our body needs is not a lump of protein like meat or a lump of carbohydrates like rice, but amino acids and glucose from which they are broken down. If proteins or carbohydrates cannot be broken down into amino acids and glucose and large chunks enter the body as a whole, our body considers them as foreign invaders or foreign substances and causes severe rejection and various allergic reactions.
If so, why is it leaking?
So what the hell is causing the leaky gut? Stress and frequent heavy drinking are the biggest causes.  When you are stressed, cortisol, the stress hormone, increases, and intestinal permeability increases. When the intestines begin to leak, factors that protect our body, such as immunoglobulin, decrease and an inflammatory response occur throughout the body. Allergies that were not there before occur, and autoimmune diseases such as arthritis and thyroid disease increase.
Excessive drinking is also prohibited
Excessive drinking also increases intestinal permeability. When the intestines start to leak due to excessive drinking, alcohol not only causes hepatitis but also endotoxins attached to the bacterial wall in the intestines attack the liver or pancreas through blood vessels. It can cause hepatitis or pancreatitis.
Be careful with drug use
In addition, aging or long-term use of drugs such as pain relievers, anti-inflammatory drugs, and antibiotics also affect intestinal permeability. In addition, if you frequently eat too much sugary food or greasy and low-fiber food, or if you are infected with a virus or bacteria, the number of beneficial bacteria in the intestine decreases, and the number of harmful bacteria increases, causing bacterial changes in the intestine, which worsens leaky gut.
Esther Lyuh, Doctor of Preventive Medicine, Seoul National University